Continuous-flow stereoselective reduction of prochiral ketones in a whole cell bioreactor with natural deep eutectic solvents

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چکیده

Immobilized whole cells of Rhodotorula rubra MIM147 were used in a packed bed flow reactor for the enantioselective reduction ?-ketonitriles and obtainment key building block synthesis antidepressant drug duloxetine.

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ژورنال

عنوان ژورنال: Green Chemistry

سال: 2022

ISSN: ['1463-9262', '1463-9270']

DOI: https://doi.org/10.1039/d1gc03786b